[Autochthonous acute viral and bacterial infections of the central nervous system (meningitis and encephalitis)].
[Autochthonous acute viral and bacterial infections of the central nervous system (meningitis and encephalitis)].
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DOI：
10.1016/s0213-005x(08)76536-4
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发表时间：
2008-07-01
影响因子：
2.5
通讯作者：
Navarro-Mari, Jose Maria
中科院分区：
文献类型：
--
作者：
Perez-Ruiz, Mercedes;Vicente, Diego;Navarro-Mari, Jose Maria
中枢神经系统急性病毒和细菌感染（脑膜炎和脑炎）的快速诊断对于患者的临床管理非常重要，有助于建立可能解决危及生命的情况的早期治疗，避免不必要的经验性治疗，减少住院时间，并促进在公共卫生背景下采取适当的干预措施。分子技术，特别是实时聚合酶链反应，已成为本土病毒性脑膜炎和脑炎最快、最灵敏的诊断方法，其在最常见的急性细菌性脑膜炎的诊断和控制中的作用变得越来越重要。自动和封闭系统可能会鼓励大多数实验室广泛和系统地使用分子技术来诊断这些神经系统综合征。
Rapid diagnosis of acute viral and bacterial infections of the central nervous system (meningitis and encephalitis) is highly important for the clinical management of the patient and helps to establish early therapy that may solve life-threatening situations, to avoid unnecessary empirical treatments, to reduce hospital stay, and to facilitate appropriate interventions in the context of public health. Molecular techniques, especially real-time polymerase chain reaction, have become the fastest and most sensitive diagnostic procedures for autochthonous viral meningitis and encephalitis, and their role is becoming increasingly important for the diagnosis and control of most frequent acute bacterial meningitides. Automatic and closed systems may encourage the widespread and systematic use of molecular techniques for the diagnosis of these neurological syndromes in most laboratories.