Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia
Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia
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DOI：
10.1097/jom.0b013e31815f889b
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发表时间：
2008-03-01
影响因子：
3.2
通讯作者：
Pavuk, Marian
中科院分区：
文献类型：
--
作者：
Michalek, Joel E.;Pavuk, Marian
背景：空军健康研究于1980年启动，作为联邦努力解决橙子剂问题的一部分。目的：研究糖尿病和癌症，并对喷洒天数、日历服务期和在东南亚（SEA）停留的时间进行额外调整。研究方法：这是一个纵向研究的退伍军人操作牧场手，单位负责喷洒剂橙子和其他2，3，7，8-四氯二苯并二恶英（TCDD）污染的除草剂在越南从1962年至1971年。结果如下：TCDD和糖尿病之间的关联和TCDD和癌症之间的牧场手退伍军人的日历期间的服务，喷洒的日子，并为癌症，在SEA花费的时间调整后，加强。结论：在空军健康研究中，服役日历期、喷洒天数和在SEA中花费的时间是重要的混杂因素。
Background: The Air Force Health Study was launched in 1980 as part of a Federal effort to resolve the Agent Orange issue. Objectives: To study diabetes and cancer with additional adjustment for days of spraying, calendar period of service, and time spent in Southeast Asia (SEA). Methods: This was a longitudinal study of veterans Of Operation Ranch Hand, the unit responsible for spraying Agent Orange and other 2,3, 7,8-tetrachlorodibenzo-p-dioxin (TCDD)-contaminated herbicides in Vietnam from 1962 to 1971. Results: Associations between TCDD and diabetes and between TCDD and cancer in Ranch Hand veterans are strengthened after adjustment for calendar period of service, days of spraying, and, for cancer, time spent in SEA. Conclusions: Calendar period of service, days of spraying, and time spent in SEA are important confounders in the Air Force Health Study.