GENETIC-ANALYSIS OF COVARIANCE STRUCTURE/E

GENETIC-ANALYSIS OF COVARIANCE STRUCTURE/E
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DOI:
10.1038/hdy.1977.9
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发表时间:
1977-01-01
期刊:
影响因子:
3.8
通讯作者:
EAVES, LJ
EAVES, LJ
中科院分区:
生物学2区
文献类型:
--
作者:
MARTIN, NG;EAVES, LJ

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The analysis of covariance structures (Joreskog, 1973) is adapted to the simultaneous maximum likelihood estimation of genetic and environmental factor loadings and specific variances. The goodness of fit is tested by .chi.2 square and SE of parameter estimates can be obtained. Any linear model used to univariate genetic analyses can be extended to the multivariate case. Most biological hypotheses about the relationships between variables can be specified by a variety of factor models. Individual parameters can be given fixed values or set to zero and hypotheses concerning the congruence of genetic and environmental correlations can be tested. The method is illustrated with published human twin data on cognitive abilities.