HOST SPECIFICITY OF DNA IN HAEMOPHILUS-INFLUENZAE - RESTRICTION AND MODIFICATION IN STRAIN RD
HOST SPECIFICITY OF DNA IN HAEMOPHILUS-INFLUENZAE - RESTRICTION AND MODIFICATION IN STRAIN RD
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DOI：
10.1016/0006-291x(72)90793-0
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发表时间：
1972-01-01
影响因子：
3.1
通讯作者：
PIEKAROWICZ, A
中科院分区：
文献类型：
--
作者：
GLOVER, SW;PIEKAROWICZ, A
流感嗜血杆菌Rd的野生型菌株由两种表型类型的细菌组成，它们限制和修饰噬菌体HP 1的能力不同。这些类别r D− m D−和r D+ m D+中的每一个都是不稳定的，并且分离了几个百分比的替代表型的染色体。此外，稳定的r D− m D−细菌在r D+ m D+培养物中自发发生，并且在r D+ m D+菌株诱变后分离出r D− m D+突变体。
Wild type strains of Haemophilus influenzae R d consist of two phenotypic classes of bacteria which differ in their abilities to restrict and modify phage HP1. Each of these classes r D− m D− and r D+ m D+ is unstable and segregates several percent of bacterla of the alternative phenotype. In addition stable r D− m D− bacteria occur spontaneously in r D+ m D+ cultures and an r D− m D+ mutant was isolated after mutagenesis of an r D+ m D+ strain.