Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs.
Drug-induced pulmonary disease. Part 2: Noncytotoxic drugs.
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DOI：
10.1164/arrd.1986.133.2.321
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发表时间：
1986-02
期刊：
影响因子：
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通讯作者：
J. A. Cooper;D. White;R. Matthay
中科院分区：
文献类型：
--
作者：
J. A. Cooper;D. White;R. Matthay
非化疗药物也可能引起肺实质改变。这些药物造成的肺损伤机制多种多样，可能涉及肺稳态的改变。非细胞毒性药物引起的肺部疾病的临床特征比细胞毒性药物相关的肺部疾病更加异质，并且几种临床综合征的表现相同。治疗和结果因每种药物和临床表现而异。第 2 部分讨论了非细胞毒性药物引起的肺部疾病的临床和致病因素。
Nonchemotherapeutic drugs may also cause pulmonary parenchymal alterations. Mechanisms of pulmonary damage by these agents are diverse and may involve alterations of pulmonary homeostasis. Clinical features of noncytotoxic, drug-induced pulmonary disease are more heterogeneous than those associated with cytotoxic drugs, and several clinical syndromes are equally represented. Treatment and outcome vary with each individual drug and clinical presentation. In part 2, clinical and pathogenic aspects of noncytotoxic, drug-induced pulmonary disease are discussed.