Dendritic cells as regulators of immune reactivity: implications for transplantation.

Dendritic cells as regulators of immune reactivity: implications for transplantation.
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DOI:
10.1097/00007890-199907150-00001
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发表时间:
1999-07
期刊:
影响因子:
6.2
通讯作者:
A. Thomson;Lina Lu
A. Thomson;Lina Lu
中科院分区:
医学2区
文献类型:
--
作者:
A. Thomson;Lina Lu

文献摘要

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树突状细胞不仅被认为是免疫反应的启动者,而且被认为是免疫反应的调节者。它们是治疗癌症、传染病和同种异体移植排斥反应中免疫反应性的潜在有力工具。我们提供了一个简短的概述树突状细胞的属性,重点是最近获得的信息,然后集中注意力在他们的能力,调节免疫反应,其相关性移植。
Dendritic cells are now regarded not only as the initiators but also as regulators of immune responses. They are potentially powerful tools for the therapeutic manipulation of immune reactivity in cancer, infectious disease, and allograft rejection. We provide a brief overview of the properties of dendritic cells, with emphasis on recently acquired information, then focus attention on their capacity to modulate immune reactivity, and its relevance to transplantation.