Pediatric myelodysplastic syndrome with inflammatory manifestations: Diagnosis, genetics, treatment, and outcome

Pediatric myelodysplastic syndrome with inflammatory manifestations: Diagnosis, genetics, treatment, and outcome
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具有炎症表现的小儿骨髓增生异常综合征:诊断、遗传学、治疗和结果

DOI:
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发表时间:
2021
影响因子:
3.2
通讯作者:
S. B. Birenboim
S. B. Birenboim
中科院分区:
医学3区
文献类型:
--
作者:
A. Yanir;A. Krauss;J. Stein;O. Steinberg;O. Gilad;S. Lotan;O. Dgany;T. Krasnov;Y. Kodman;Tamar Feuerstein;Jacques Mardoukh;H. Fishman;I. Geron;J. Yacobovich;H. Tamary;Y. Birger;G. Avrahami;S. Izraeli;S. B. Birenboim

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骨髓增生异常综合征 (MDS) 成年患者的炎症表现 (IM) 已得到充分描述,但其表现变化很大,且不存在标准化治疗方法。这种现象在儿童中很少有报道。随着越来越多的儿科患者成为造血干细胞移植 (HSCT) 候选者,应明确抗炎治疗与 HSCT 相关的作用。
Inflammatory manifestations (IM) are well described in adult patients with myelodysplastic syndrome (MDS), but the presentation is highly variable and no standardized treatment exists. This phenomenon is rarely reported in children. As more pediatric patients are hematopoietic stem cell transplantation (HSCT) candidates, the role of anti‐inflammatory treatment in relation to HSCT should be defined.
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