Diagnostic differences in social anhedonia: A longitudinal study of schizophrenia and major depressive disorder
Diagnostic differences in social anhedonia: A longitudinal study of schizophrenia and major depressive disorder
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DOI：
10.1037//0021-843x.110.3.363
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发表时间：
2001-08-01
影响因子：
4.6
通讯作者：
Brown, SA
中科院分区：
文献类型：
--
作者：
Blanchard, JJ;Horan, WP;Brown, SA
本研究检验了这一假设，即在精神分裂症中，特质性社交快感缺失（SA）的升高是一个稳定的个体差异，而在抑郁症中，SA的增加是当前临床状态的反映，随着恢复而减少。此外，还研究了消极情感（NA）和积极情感（PA）的特质差异。在住院期间对精神分裂症（n = 55）和抑郁症（n = 34）患者进行基线评估，并与非精神病对照组（n = 41）进行比较。在1年随访时再次对参与者进行评估。在基线时，与对照组相比，精神分裂症和抑郁症患者的特征都是SA升高，NA更大，PA更低。在精神分裂症患者中，SA升高在随访期间保持稳定。然而，在康复的抑郁症患者中，SA在随访期间下降。在1年随访期间，NA和PA的组间差异仍然存在。这些结果支持这样的观点，即SA升高是持久的精神分裂症，但SA升高是短暂的抑郁症的临床状态。
This study examined the hypothesis that, in schizophrenia, elevated trait social anhedonia (SA) is a stable individual difference, whereas in depression, increased SA is a reflection of a current clinical state that will diminish with recovery. Differences in trait Negative Affect (NA) and Positive Affect (PA) were also examined. Individuals with schizophrenia (n = 55) and depression (n = 34) were evaluated at baseline during hospitalization and compared with nonpsychiatric control participants (n = 41). Participants were assessed again at a 1-year follow-up. At baseline, compared with control participants, individuals with schizophrenia and depression were both characterized by elevated SA, greater NA, and lower PA. In schizophrenic individuals, elevated SA remained stable over the follow-up. However, in recovered depressed patients, SA declined over the follow-up period. Group differences remained in NA and PA over the 1-year follow-up. These results support the view that elevated SA is enduring in schizophrenia but that elevated SA is transiently related to clinical status in depression.