The role of frozen section biopsy for submandibular gland tumors.
The role of frozen section biopsy for submandibular gland tumors.
复制标题
冰冻切片活检在颌下腺肿瘤中的作用。
DOI：
10.1080/00016489.2021.1946137
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Murono S.
中科院分区：
文献类型：
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作者：
Suzuki M;Nakaegawa Y;Kawase T;Ikeda M;Murono S.
背景尽管已有几篇关于冷冻切片活检（FSB）对腮腺肿瘤诊断准确性的报道，目的：探讨FSB对下颌下腺肿瘤（SGT）诊断的必要性。材料与方法：对42例SGT患者行细针穿刺细胞学检查（FNAC），2005年至2020年期间，结果38例恶性肿瘤患者中，除4例不确定的细针吸细胞学检查外，细针吸细胞学检查的敏感性和特异性分别为0和97%，细针吸细胞学检查的敏感性和特异性分别为100和97%。考虑到4例FNAC不确定为恶性的病例，FNAC诊断恶性肿瘤的敏感性和特异性分别为50%和92%，FSB为100%和95%。
BackgroundAlthough there have been several reports of the diagnostic accuracy of frozen section biopsy (FSB) for parotid gland tumors, few studies have focused on its diagnostic accuracy for submandibular gland tumors.Aim/objectivesThis study aimed to investigate the necessity of FSB with regard to its diagnostic accuracy for submandibular gland tumors (SGTs).Materials and methodsAbout 42 SGT patients underwent both fine-needle aspiration cytology (FNAC) and FSB between 2005 and 2020. The results of FNAC and FSB were analyzed and compared with the final histological diagnoses.ResultsThe respective sensitivity and specificity in detecting malignant tumors in 38 cases, excluding the four indeterminate FNAC cases, they were 0 and 97% for FNAC, and 100 and 97% for FSB. Considering the four indeterminate FNAC cases to be malignant, the respective sensitivity and specificity in detecting malignant tumors in the 42 cases were 50 and 92% for FNAC, and 100 and 95% for FSB.Conclusions and significanceFSB may be useful for malignancy detection as a final histological diagnosis in cases that are diagnosed as benign or indeterminate by FNAC in SGTs.