Importance of the renin system for determining blood pressure fall with acute salt restriction in hypertensive and normotensive whites
Importance of the renin system for determining blood pressure fall with acute salt restriction in hypertensive and normotensive whites
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DOI：
10.1161/01.hyp.38.3.321
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发表时间：
2001-09-01
期刊：
影响因子：
8.3
通讯作者：
MacGregor, GA
中科院分区：
文献类型：
--
作者：
He, FJ;Markandu, ND;MacGregor, GA
高血压（n=93）和正常血压（n=39）的白人受试者在5天内摄入约350 mmol/d的高钠，然后在5天内摄入10至20 mmol/d的低钠。随着盐摄入量的急剧减少，正常血压组的血压没有明显变化，但高血压组的血压有所下降。与正常受试者相比，高血压患者的血压下降幅度大7/7毫米汞柱(P
Hypertensive (n=93) and normotensive (n=39) white individuals were given a high sodium intake of approximate to 350 mmol/d for 5 days followed by a low sodium intake of 10 to 20 mmol/d for 5 days. With this acute and large reduction in salt intake, no significant change was seen in blood pressure in the normotensive individuals, but blood pressure decreased in the hypertensive individuals. Compared with normotensive subjects, hypertensive patients had a 7/7-mm Hg greater fall in blood pressure (P