A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells

A highly sensitive near-infrared fluorescent probe for cysteine and homocysteine in living cells
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一种高灵敏度近红外荧光探针,用于检测活细胞中的半胱氨酸和同型半胱氨酸

DOI:
10.1039/c3cc45519j
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发表时间:
2013-01-01
影响因子:
4.9
通讯作者:
Tang, Bo
Tang, Bo
中科院分区:
化学2区
文献类型:
--
作者:
Kong, Fanpeng;Liu, Renpu;Tang, Bo

文献摘要

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设计并合成了一种近红外荧光探针(Cy-O-CHO),用于检测活细胞中的内源性半胱氨酸/同型半胱氨酸。在生理条件下,Cy-O-CHO对Cys/Hcy具有较高的灵敏度和良好的选择性,Cys的检测限为7.9 nM。
A near-infrared fluorescent probe (Cy-O-CHO) for the detection of endogenous Cys/Hcy in living cells was designed and synthesized. Cy-O-CHO exhibited high sensitivity and good selectivity to Cys/Hcy under physiological conditions with a detection limit of 7.9 nM for Cys.