Afterhyperpolarization conductance time course in lumbar motoneurones of the cat.
Afterhyperpolarization conductance time course in lumbar motoneurones of the cat.
复制标题
猫腰椎运动神经元的超极化后电导时间过程。
DOI：
10.1111/j.1748-1716.1974.tb05707.x
复制
发表时间：
1974
期刊：
影响因子：
--
通讯作者：
B. Gustafsson
中科院分区：
文献类型：
--
作者：
F. Baldissera;B. Gustafsson
本文研究了猫α-运动神经元长时后超极化（AHP）电导过程的时间和电位依赖性。电导的变化通过注入短电流脉冲来确定。电导时间过程的特征在于由对应于AHP的较慢超极化阶段的平台中断的持久指数衰减。通过在阈下区域中注入持久的电流脉冲来置换膜电位，发现电导在很大程度上不受膜电位位移的影响。当从AHP电压计算AHP电导时间过程时，发现了类似的特征。得出的结论是，运动神经元中的层次分析法是由具有复杂S形时间过程的钾电导过程给出的。给出了描述这一时间过程的数学表达式。
The time and potential dependence of the conductance process (es) underlying the longlasting afterhyperpolarization (AHP) in the cat's a-motoneurones were studied. The conductance changes were determined by injection of short current pulses. The conductance time course was characterized by a longlasting exponential decay interrupted by a plateau corresponding to the slower hypcrpolarizing phase of the AHP. By displacing the membrane potential in the subthreshold region with the injection of longlasting current pulses it was found that the conductance was largely unaffected by membrane potential displacements. Similar characteristics were found when calculating the AHP conductance time course from the AHP voltage. It was concluded that the AHP in motoneurones is given by a potassium conductance process with this complex S-shaped time course. A mathematical expression describing this time course is given.