Chemical Composition, Enantiomeric Distribution and AChE-BChE Activities of the Essential Oil of Myrteola phylicoides (Benth) Landrum from Ecuador
Chemical Composition, Enantiomeric Distribution and AChE-BChE Activities of the Essential Oil of Myrteola phylicoides (Benth) Landrum from Ecuador
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DOI：
10.25135/rnp.112.18.09.893
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发表时间：
2019-07-01
影响因子：
1.9
通讯作者：
Armijos, Chabaco
中科院分区：
文献类型：
--
作者：
Calva, James;Castillo, Jessica M.;Armijos, Chabaco
采用水蒸气蒸馏法对厄瓜多尔产桃金娘挥发油进行了化学成分分析。共鉴定出37种化合物，占挥发油总含量的90.30%。单萜类化合物占53.06%，倍半萜类化合物占35.24%。主要成分为α-蒎烯（30.94%）、（E）-香芹烯（21.93%）、β-蒎烯（14.45%）和α-蛇麻烯（9.56%）。提取M.叶状囊藻体外抗AChE抑制活性较弱，IC 50值为60.8 μ g/mL，BChE活性较低，IC 50值>250 μ g/mL。这是首次报道该种精油的化学成分。
The volatile constituents of the essential oil (EO) Myrteola phylicoides (Benth) Landrum, from Ecuador, extracted by steam distillation have been analyzed. A total of 37 compounds, representing 90.30% the total essential oil sample were identified. Monoterpenes hydrocarbons (53.06%) and sesquiterpene hydrocarbons (35.24%) were the principal groups of compounds. The major components were identified as alpha-pinene (30.94%), (E)-caryophyllene (21.93%), beta-pinene (14.45%) and alpha-humulene (9.56%). The essential oil of M. phylicoides showed weak in vitro activity against AChE inhibition with IC50 value 60.8 mu g/mL and a low BChE activity with IC50 value >250 mu g/mL. This is the first report on the chemical composition of the essential oil of this species.