Rapid detection of drug metabolites in latent fingermarks
Rapid detection of drug metabolites in latent fingermarks
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DOI：
10.1039/b816273e
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发表时间：
2009-01-01
期刊：
影响因子：
4.2
通讯作者：
Russell, David A.
中科院分区：
文献类型：
--
作者：
Hazarika, Pompi;Jickells, Sue M.;Russell, David A.
用抗可替宁抗体功能化的磁性颗粒已被用于通过检测沉积在吸烟者指纹内的汗液中的可替宁抗原来对潜在指纹进行成像。抗体-磁性颗粒缀合物容易地应用于潜在指纹，而过量的试剂通过使用磁棒被去除。结果表明，药物代谢物，如可替宁，可以被检测到并用于指纹成像，以在15分钟内确定个人的身份。
Magnetic particles functionalised with anti-cotinine antibody have been used to image latent fingermarks through the detection of the cotinine antigen in the sweat deposited within the fingerprints of smokers. The antibody-magnetic particle conjugates are readily applied to latent fingerprints while excess reagents are removed through the use of a magnetic wand. The results have shown that drug metabolites, such as cotinine, can be detected and used to image the fingermark to establish the identity of an individual within 15 minutes.