General mechanism of actomyosin contractility.
General mechanism of actomyosin contractility.
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DOI：
10.1103/physrevlett.107.118101
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发表时间：
2011-09-09
影响因子：
8.6
通讯作者：
Carlsson AE
中科院分区：
文献类型：
--
作者：
Dasanayake NL;Michalski PJ;Carlsson AE
通过模拟肌球蛋白微丝在随机肌动蛋白网络中的运动，分析了肌球蛋白微丝产生的应力。应力是压倒性的收缩，因为具有收缩应力的微丝平衡位置具有比膨胀应力的微丝平衡位置低的能量。力链导致意外的大应力。
Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile, because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.