Platelet-derived microparticles during and after acute coronary syndrome

Platelet-derived microparticles during and after acute coronary syndrome
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DOI:
10.1160/th11-11-0779
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发表时间:
2012-06-01
影响因子:
6.7
通讯作者:
Wallen, Hakan
Wallen, Hakan
中科院分区:
医学2区
文献类型:
--
作者:
Skeppholm, Mika;Mobarrez, Fariborz;Wallen, Hakan

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由于微粒在血小板激活时脱落,并可用于评估血小板功能,我们测量了急性冠脉综合征(ACS)期间和之后血浆中血小板衍生微粒(PMPs)的浓度。51例急性冠脉综合征患者在入院时、24小时内(冠状动脉造影术前)和6个月后进行了调查。对61名性别和年龄匹配的健康对照进行了一次调查。PMP被定义为颗粒
As microparticles are shedded upon platelet activation, and may be used to assess platelet function, we measured plasma concentrations of platelet-derived microparticles (PMPs) during and after an acute coronary syndrome (ACS). Fifty-one patients with ACS were investigated at admission, within 24 hours (before coronary angiography), and six months later. Sixty-one sex- and age-matched healthy controls were investigated once. PMPs were defined as particles