Synthesis of Low-Dimensional Polyion Complex Nanomaterials via Polymerization-Induced Electrostatic Self-Assembly
Synthesis of Low-Dimensional Polyion Complex Nanomaterials via Polymerization-Induced Electrostatic Self-Assembly
复制标题
聚合诱导静电自组装合成低维聚离子复合纳米材料
DOI：
10.1002/anie.201710811
复制
发表时间：
2018-01-22
影响因子：
16.6
通讯作者：
Cai, Yuanli
中科院分区：
文献类型：
--
作者：
Ding, Yi;Cai, Meng;Cai, Yuanli
纳米结构的聚离子复合物在生物材料中有着广泛的应用。然而，传统的组装在放大和再现性方面存在弱点。迄今为止，只有少数低维PIC可用。在这里，我们报告了一个有效的和可扩展的策略来制备低维PIC库。它涉及在25 ° C下在水中以5- 50%w/w总固体浓度存在相反电荷的聚离子的情况下离子单体的可见光介导的RAFT聚合，即聚合诱导的静电自组装（PIESA）。在水中可以获得囊泡、多室囊泡和大面积单层纳米膜。在甲醇/水溶液中可以制备出长的纳米线和多孔纳米薄膜。报道了一种不寻常的单分子聚离子复合物（uPIC）-球-支/网-膜转变。这种绿色化学提供了一个通用的平台，以制备各种低维PIC与高再现性的商业上可行的规模下，生态友好的条件。
Nanostructured polyion complexes (PICs) are appealing in biomaterials applications. Yet, conventional assembly suffers from the weakness in scale-up and reproducibility. Only a few low-dimensional PICs are available to date. Herein we report an efficient and scalable strategy to prepare libraries of low-dimensional PICs. It involves a visible-light-mediated RAFT polymerization of ionic monomer in the presence of a polyion of the opposite charge at 5-50% w/w total solids concentration in water at 25 degrees C, namely, polymerization-induced electrostatic self-assembly (PIESA). A Vesicle, multi-compartmental vesicle, and large-area unilamellar nano-film can be achieved in water. A long nanowire and porous nanofilm can be prepared in methanol/water. An unusual unimolecular polyion complex (uPIC)-sphere-branch/network-film transition is reported. This green chemistry offers a general platform to prepare various low-dimensional PICs with high reproducibility on a commercially viable scale under eco-friendly conditions.