Evaluation of dermal patterns in Down's syndrome by predictive discrimination

Evaluation of dermal patterns in Down's syndrome by predictive discrimination
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通过预测辨别评估唐氏综合症的皮肤模式

DOI:
10.1111/j.1399-0004.1971.tb00273.x
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发表时间:
1971
期刊:
影响因子:
3.5
通讯作者:
M. Davis
M. Davis
中科院分区:
医学2区
文献类型:
--
作者:
D. Bolling;Digamber S. Borgaonkar;Helen M. Herr;M. Davis

文献摘要

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在唐氏综合征患者和对照组中检查了左右皮肤图案区域的独立性。然后开发一个综合评分作为实验室测试,以确认唐氏综合征的临床诊断。该分数通过正确地对97.7%的受试个体进行评分而证明了更好的区分度,而单一模式评分方法正确地得分为96.6%。通过使用综合分数,也获得了简单的元素。它部分地纠正了由于两侧图案出现的相关性而引起的误差。
Independence of left and right dermal pattern areas were examined in Down's syndrome patients and controls. A composite score was then developed as a laboratory test to confirm the clinical diagnosis of Down's syndrome. The score demonstrates better discrimination by correctly scoring 97.7% of the individuals tested whereas the single pattern scoring method correctly scored 96.6%. An element of simplicity is also gained by using composite scores. It corrects in part the error due to correlation of the occurrence of patterns on the two sides.