A dominant lethal study in male rats after repeated exposures to vinyl chloride or vinylidene chloride.

A dominant lethal study in male rats after repeated exposures to vinyl chloride or vinylidene chloride.
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一项针对雄性大鼠反复接触氯乙烯或偏二氯乙烯后的显性致死研究。

DOI:
10.1080/15287397709529630
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发表时间:
1977
期刊:
Journal of toxicology and environmental health
影响因子:
--
通讯作者:
Cheng
Cheng
中科院分区:
--
文献类型:
--
作者:
Robert D. Short;J. Minor;Joseph M. Winston;Cheng

文献摘要

被引文献

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Male CD rats were exposed 6 hr/day for 5 days/wk to 0, 50, 250, or 1,000 ppm of vinyl chloride or 55 ppm of vinylidene chloride. Starting on week 11 of exposure, these males were mated with untreated females. There was no evidence of either preimplantation loss or postimplanation loss in pregnant females that resulted from these matings. Consequently, it was concluded that these exposures did not produce germinal mutation, as manifested by a dominant lethal effect, in male rats.