Knee osteoarthritis and body mass index: a population-based case control study
Knee osteoarthritis and body mass index: a population-based case control study
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DOI：
10.1080/03009740510017922
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发表时间：
2005-02-01
影响因子：
2.1
通讯作者：
Thelin, N
中科院分区：
文献类型：
--
作者：
Holmberg, S;Thelin, A;Thelin, N
目的：众所周知，超重与膝骨关节炎有关。本研究的目的是调查正常体重范围内男性和女性患膝骨关节炎的风险与体重指数 (BMI) 的关系，并评估以前体重与当前体重的影响。 方法：在瑞典南部进行了一项基于人群的病例对照研究，包括 825 例经 X 射线证实的股骨关节炎病例和 825 例年龄、性别和县匹配的人群对照。收集有关体重、身高和混杂因素（遗传、吸烟、膝盖受伤和体力活动）的邮寄问卷数据，并使用逻辑回归模型进行分析。响应频率为 89%。 结果：参与者的平均年龄为 63 岁，其中 57% 为女性。当前 BMI 为 23 至 23 的男性中，调整后的膝骨关节炎风险增加了四倍
Objective: It is well established that overweight is related to osteoarthritis of the knees. The aim of this study was to investigate the risk of knee osteoarthritis for men and women in relation to body mass index (BMI) within the normal weight range and to assess the effect of former versus current weight.Methods: A population-based case - control study was carried out in the southern part of Sweden, including 825 cases with X-ray verified femorotibial osteoarthritis and 825 age-, sex-, and county-matched population controls. Mailed questionnaire data on weight, height, and confounding factors ( heredity, smoking, knee injuries, and physical activity) were collected and analysed using logistic regression models. The response frequency was 89%.Results: Mean age of the participants was 63 years, and 57% were women. The adjusted risk of knee osteoarthritis was increased fourfold in men with a current BMI 23 to