Early-life risk factors for late-onset depression.
Early-life risk factors for late-onset depression.
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晚发性抑郁症的早期危险因素。
DOI：
10.1002/gps.1727
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发表时间：
2007
影响因子：
4
通讯作者：
Cohen,Patricia
中科院分区：
文献类型：
--
作者：
Sneed,JoelR;Kasen,Stephanie;Cohen,Patricia
目的比较无抑郁史(无MDD)、早发性抑郁症(EOD)和迟发性抑郁症(LOD)妇女在心理社会危险因素(婚姻冲突和缺乏社会支持)、神经质和总体自评健康方面的差异。然后在诊断前大约10年对这些组在心理社会、个性和总体健康风险评估方面进行比较。结果两组之间在婚姻冲突和社会支持方面没有差异。有EOD组的神经质得分高于LOD组和无MDD组。重要的是，那些患有LOD的人在确诊前10年报告的健康状况比那些没有MDD的人更差。结论这些发现支持这样的观点，即健康状况不佳，而不是心理社会危险因素或神经质，使其他健康的成年人在晚年第一次患上抑郁症。版权所有©2006 John Wiley&Sons，Ltd.
ObjectiveTo assess differences between women with no history of depression (No MDD), early‐onset depression (EOD), and late‐onset depression (LOD) on psychosocial risk factors (marital conflict and lack of social support), neuroticism, and overall self‐rated health.MethodDiagnostic data from a community‐based longitudinal study of women at mean ages 39, 42, 48, and 59 was used to create three groups of women (No MDD, EOD and LOD). These groups were then compared on psychosocial, personality, and overall health risk assessed approximately 10 years prior to diagnosis.ResultsThere were no differences between the groups on marital conflict and social support. Those with EOD scored higher than those in the LOD and No MDD groups on neuroticism. Importantly, those with LOD reported poorer health than those with No MDD 10 years prior to diagnosis.ConclusionsThese findings provide support for the notion that poor health and not psychosocial risk factors or neuroticism predispose otherwise healthy adults to developing depression for the first time in late‐life. Copyright © 2006 John Wiley & Sons, Ltd.