Efficient use of continuous, real-time prostate localization
Efficient use of continuous, real-time prostate localization
复制标题
有效利用连续、实时前列腺定位
DOI：
--
复制
发表时间：
2008
影响因子：
3.5
通讯作者：
P. Parikh
中科院分区：
文献类型：
--
作者：
K. Malinowski;C. Noel;M. Roy;T. Willoughby;Toufik Djemi;S. Jani;T. Solberg;David M. Liu;L. Levine;P. Parikh
最近的技术进步使得在放疗过程中监测前列腺运动成为可能。利用先前发表的来自35名在前列腺癌治疗期间接受持续定位的患者的数据，我们模拟了各种干预措施，以确定最小延长完成日常治疗时间的辐射门控和患者重新定位策略。可接受的反应方案是那些至少95%的患者的前列腺在至少95%的时间内保持在计划范围内的方案。对于7或10毫米的边缘，不需要门控和重新定位，因为这些边缘很少发生偏移。然而，对于3和5毫米的切缘，常规干预是必要的。在模拟干预中，治疗师可以在不进入房间的情况下重新定位治疗沙发，最省时的反应方案是在前列腺位置超出治疗范围后立即重新定位沙发。在模拟中，治疗师必须进入房间重新定位沙发，在中断治疗以重新定位治疗沙发之前，通过手动控制治疗分别为3毫米和5毫米的间隙进行11秒和21秒的治疗，可以减少总体治疗时间，提高准确性。
Recent technological advances make it possible to monitor prostate movement during radiation delivery. Using previously published data from 35 patients who underwent continuous localization during prostate cancer treatment, we simulated various interventions to identify the radiation-gating and patient-repositioning strategies that least prolonged the time to complete the daily treatment. Acceptable response protocols were those that resulted in at least 95% of patients' prostates remaining within the planning margins at least 95% of the time. Gating and repositioning were not necessary for margins of 7 or 10 mm because of the rarity of excursions at these margins. However, intervention was routinely necessary for margins of 3 and 5 mm. In simulated interventions for which the therapist could reposition the treatment couch without entering the room, the most time-efficient response protocol was to reposition the couch immediately after the prostate position was outside the treatment margins. In simulations in which the therapist had to enter the room to reposition the couch, overall treatment time could be reduced and accuracy could be increased by manually gating treatment for 11 and 21 s for 3- and 5-mm margins, respectively, before interrupting treatment to reposition the treatment couch.
DOI：
10.1016/j.ijrobp.2003.10.017
发表时间：
2005-06-01
影响因子：
7
作者：
Ghilezan, MJ;Jaffray, DA;Martinez, AA
通讯作者：
Martinez, AA
DOI：
10.1016/j.ijrobp.2005.12.033
发表时间：
2006-06-01
影响因子：
7
作者：
Litzenberg, DW;Balter, JM;Levine, L
通讯作者：
Levine, L