Participation of the prefrontal cortices in prospective memory: evidence from a PET study in humans

Participation of the prefrontal cortices in prospective memory: evidence from a PET study in humans
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DOI:
10.1016/s0304-3940(98)00628-4
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发表时间:
1998-09-04
影响因子:
2.5
通讯作者:
Fukuda, H
Fukuda, H
中科院分区:
医学4区
文献类型:
--
作者:
Okuda, J;Fujii, T;Fukuda, H

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前瞻记忆是人类的一种记忆特征,它涉及记住未来要做的事情的活动。本研究首次提供了前瞻记忆的功能神经解剖学。我们使用正电子发射断层扫描(PET),发现了几个与前瞻性记忆任务有关的局部脑激活,这些任务是在执行正在进行的日常活动时保留和记住计划的行动所必需的。激活被确定在右背外侧和腹外侧前额叶皮质,左额极和前扣带回,左海马旁回,和中线内侧额叶。我们将这些激活归因于前瞻记忆中涉及的几个认知过程,例如对未来行为的意图,检查当前刺激中的目标项目,以及在计划的行动和日常活动之间分配注意力。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
Prospective memory is a memory feature in humans which involves activities for remembering to do something in the future. The present study provides functional neuroanatomy of prospective memory for the first time. We used positron emission tomography (PET) and found several localized brain activations in relation to a prospective memory task required to retain and remember a planned action while performing an ongoing routine activity. Activations were identified in the right dorsolateral and ventrolateral prefrontal cortices, the left frontal pole and anterior cingulate gyrus, the left parahippocampal gyrus, and midline medial frontal lobe. We attributed these activations to several cognitive processes involved in prospective memory, such as holding an intention toward future behavior, checking target items within presented stimuli, and dividing attention between the planned action and the routine activity. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.