Full Characterization of in vivo Muscle as an Elastic, Incompressible, Transversely Isotropic Material Using Ultrasonic Rotational 3D Shear Wave Elasticity Imaging.
Full Characterization of in vivo Muscle as an Elastic, Incompressible, Transversely Isotropic Material Using Ultrasonic Rotational 3D Shear Wave Elasticity Imaging.
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DOI：
10.1109/tmi.2021.3106278
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发表时间：
2022-01
影响因子：
10.6
通讯作者：
Nightingale KR
中科院分区：
文献类型：
--
作者：
Knight AE;Trutna CA;Rouze NC;Hobson-Webb LD;Caenen A;Jin FQ;Palmeri ML;Nightingale KR
使用3D旋转剪切波弹性成像（SWEI）设置，在健康志愿者的股外侧肌中采集3D剪切波数据。换能器面和肌肉纤维之间的先天倾斜导致多个剪切波模式的激发，从而允许将肌肉更完整地表征为弹性、不可压缩、横向各向同性（ITI）材料。测量剪切垂直（SV）和剪切水平（SH）波速的能力允许测量完整ITI材料表征所需的三个独立参数：纵向剪切模量μL、横向剪切模量μT和拉伸各向异性χE。在此，我们开发并验证了估计这些参数的方法，并在体内测量它们，在放松的股外侧肌中，μL = 5.77 ± 1.00 kPa，μT = 1.93 ± 0.41 kPa（给出剪切各向异性χμ = 2.11 ± 0.92），χE = 4.67 ± 1.40。我们还证明，3D SWEI可以用来更准确地表征肌肉的力学性能相比，2D SWEI。
Using a 3D rotational shear wave elasticity imaging (SWEI) setup, 3D shear wave data were acquired in the vastus lateralis of a healthy volunteer. The innate tilt between the transducer face and the muscle fibers results in the excitation of multiple shear wave modes, allowing for more complete characterization of muscle as an elastic, incompressible, transversely isotropic (ITI) material. The ability to measure both the shear vertical (SV) and shear horizontal (SH) wave speed allows for measurement of three independent parameters needed for full ITI material characterization: the longitudinal shear modulus μL, the transverse shear modulus μT, and the tensile anisotropy χE. Herein we develop and validate methodology to estimate these parameters and measure them in vivo, with μL = 5.77 ± 1.00 kPa, μT = 1.93 ± 0.41 kPa (giving shear anisotropy χμ = 2.11 ± 0.92), and χE = 4.67 ± 1.40 in a relaxed vastus lateralis muscle. We also demonstrate that 3D SWEI can be used to more accurately characterize muscle mechanical properties as compared to 2D SWEI.