Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila tenm/odd Oz gene, in the central nervous system
Compartmentalized expression of zebrafish ten-m3 and ten-m4, homologues of the Drosophila tenm/odd Oz gene, in the central nervous system
复制标题
DOI：
10.1016/s0925-4773(99)00155-0
复制
发表时间：
1999-09-01
影响因子：
2.6
通讯作者：
Okamoto, H
中科院分区：
文献类型：
--
作者：
Mieda, M;Kikuchi, Y;Okamoto, H
斑马鱼Ten-M3和Ten-M4编码的蛋白质与果蝇配对基因ten(M)/odz(Odz)的产物高度相似。他们的产品包含八个类似表皮生长因子(EGF)的重复序列，与细胞外基质分子Tenascin的重复序列非常相似。在节段期，Ten-M3在体节、脊索、咽弓和脑中表达，而Ten-M4主要在脑中表达。在发育中的大脑中，Ten-M3和Ten-M4的表达描绘了几个区块。有趣的是，Ten-M3和Ten-M4在发育中的前脑和中脑中沿喙尾轴和背腹轴显示出互补的表达模式，这取决于发育阶段和位置。(C)1999爱思唯尔爱尔兰科学有限公司。保留所有权利。
Zebrafish ten-m3 and ten-m4 encode proteins highly similar to the product of Drosophila pair-rule gene ten(m)/odd Oz (odz). Their products contain eight epidermal growth factor (EGF)-like repeats that resemble mostly those of the extracellular matrix molecule tenascin. During segmentation period, ten-m3 is expressed in the somites, notochord, pharyngeal arches, and the brain, while expression of ten-m4 is mainly restricted to the brain. In the developing brain, ten-m3 and ten-m4 expression delineates several compartments. Interestingly, ten-m3 and ten-m4 show expression patterns complementary to each other in the developing forebrain and midbrain along both rostrocaudal and dorsoventral axes, depending on developmental stages and locations. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.