Density-wave theory of the capsid structure of small icosahedral viruses
Density-wave theory of the capsid structure of small icosahedral viruses
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DOI：
10.1103/physrevlett.98.185502
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发表时间：
2007-05-04
影响因子：
8.6
通讯作者：
Rochal, S. B.
中科院分区：
文献类型：
--
作者：
Lorman, V. L.;Rochal, S. B.
我们应用朗道结晶理论来解释和分类具有球形拓扑和二十面体对称性的小病毒的衣壳结构。我们开发了一种明确的方法来预测构成病毒衣壳的蛋白质的质心位置。产生位置的相应密度分布函数具有通用形式，不需要任何拟合参数。该理论统一地描述了满足著名的Caspar和Klug结构几何模型的结构和违反该模型的结构。
We apply Landau theory of crystallization to explain and to classify the capsid structures of small viruses with spherical topology and icosahedral symmetry. We develop an explicit method which predicts the positions of centers of mass for the proteins constituting the viral capsid shell. Corresponding density distribution function which generates the positions has a universal form without any fitting parameter. The theory describes in a uniform way both the structures satisfying the well-known Caspar and Klug geometrical model for capsid construction and those violating it.