Palladium-Catalyzed Synthesis of 3,6-Diaryl-1-silylfulvenes: A Promising Entry for Preparing 1,3,6-Triarylfulvenes Bearing Three Different Aryl Groups
Palladium-Catalyzed Synthesis of 3,6-Diaryl-1-silylfulvenes: A Promising Entry for Preparing 1,3,6-Triarylfulvenes Bearing Three Different Aryl Groups
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钯催化合成 3,6-二芳基-1-甲硅烷基富烯：制备带有三种不同芳基的 1,3,6-三芳基富烯的一个有前景的切入点
DOI：
10.1021/acs.orglett.3c00340
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发表时间：
2023
期刊：
影响因子：
5.2
通讯作者：
Hidenori Kinoshita,* and Katsukiyo Miura
中科院分区：
文献类型：
--
作者：
Hayato Ohki;Hidenori Kinoshita,* and Katsukiyo Miura
我们开发了一种合成方法来制备含有三个不同芳基的(E)-1,3,6-三芳基fulvenes。在钯催化剂的作用下，1,4-二芳基-1-溴-1,3-丁二烯与硅基乙炔反应，得到了收率较高的(E)-3,6-二芳基-1-硅基fulvenes。得到的（异丙氧基）硅基黄烯转化为含有不同类型芳基取代基的(E)-1,3,6-三芳基黄烯。(E)-3,6-二芳基-1-硅基fulvenes是合成多种(E)-1,3,6-三芳基fulvenes的有前途的模板。
We developed a synthetic methodology for preparing (E)-1,3,6-triarylfulvenes bearing three different aryl groups. The reaction of 1,4-diaryl-1-bromo-1,3-butadienes with silylacetylenes in the presence of a palladium catalyst produced (E)-3,6-diaryl-1-silyl-fulvenes in good to excellent yields. The (isopropoxy)silylated fulvenes thus obtained were converted to (E)-1,3,6-triarylfulvenes bearing different types of aryl substituents. (E)-3,6-Diaryl-1-silyl-fulvenes are promising templates for the synthesis of diverse (E)-1,3,6-triarylfulvenes.