Palladium-catalyzed coupling reactions of bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene to (3,4-dihydroxyalkenyl)benzaldehydes in the synthesis of lipoxin analogues
Palladium-catalyzed coupling reactions of bromobenzaldehydes with 3,4-di(tert-butyldimethylsilyloxy)-1-alkene to (3,4-dihydroxyalkenyl)benzaldehydes in the synthesis of lipoxin analogues
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DOI：
10.1016/s0040-4039(97)10801-2
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发表时间：
1998-02-26
影响因子：
1.8
通讯作者：
Kurozumi, S
中科院分区：
文献类型：
--
作者：
Nokami, J;Furukawa, A;Kurozumi, S
通过钯催化的Heck型偶联反应，邻、间、对溴苯甲醛分别与3，4-二（叔丁基二甲基硅氧基）-1-烯烃选择性地合成了邻、间、对（3，4-二羟基烯基）苯甲醛。产物用于合成脂氧素类似物，o-，m-和p-3-羟基烯基-3，4-二羟基烯基苯。(C)1998爱思唯尔科技有限公司版权所有。
o-, m-, and p-(3, 4-Dihydroxyalkenyl)benzaldehydes were selectively prepared via palladium-catalyzed Heck-type coupling reactions of o-, m-, and p-bromobenzaldehydes with 3, 4-di(tert-butyldimethylsilyloxy)-1-alkene. The products were employed for the synthesis of lipoxin analogues, o-, m-, and p-3-hydroxyalkenyl-3, 4-dihydroxyalkenylbenzenes. (C) 1998 Elsevier Science Ltd. All rights reserved.