Aetiology of acute leukaemia
Aetiology of acute leukaemia
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DOI：
10.1016/s0140-6736(96)09412-3
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发表时间：
1997-02-01
期刊：
影响因子：
168.9
通讯作者：
Greaves, MF
中科院分区：
文献类型：
--
作者：
Greaves, MF
电离辐射。在高剂量和急性照射下，是与白血病发生有关的一个因素，但有什么证据表明白血病发生与诊断X射线、天然陆地或宇宙电离辐射、电磁场或核能的照射有关？为什么人口混合和感染是塞拉菲尔德和敦雷核处理厂周围儿童急性白血病聚集的可能解释？这些问题，以及如何化学试剂，包括治疗物质，可能有助于白血病，在这最后一篇文章中讨论白血病系列。
Ionising radiation. In high dose and with acute exposure, is a factor that has been implicated in leukaemogenesis, but what is the evidence for leukaemogenesis and exposure to diagnostic X-rays, to natural terrestrial or cosmic ionising radiation, to electromagnetic fields, or to nuclear energy? Why is population mixing and infection a possible explanation for the clusters of childhood acute leukaemias around the nuclear processing plants of Sellafield and Dounreay? These questions, as well as how chemical agents, including therapeutic substances, might contribute to leukaemogenesis, are discussed in this last article in the leukaemia series.