The use of antibiotics in cattle in North-East Benin: pharmaceutical inventory and risk practices of cattle breeders
The use of antibiotics in cattle in North-East Benin: pharmaceutical inventory and risk practices of cattle breeders
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DOI：
10.1007/s11250-018-1612-9
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发表时间：
2018-10-01
影响因子：
1.7
通讯作者：
Youssao, A. K. I.
中科院分区：
文献类型：
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作者：
Dognon, S. R.;Antoine-Moussiaux, N.;Youssao, A. K. I.
这项研究的目的是清点贝宁东北部牛中使用的抗生素，并评估可能导致抗生素残留污染食物链以及动物和人类中耐抗生素细菌选择的风险做法。对贝宁北部Banikoara、Kandi、benmbereke和Kalale地区的98名养牛者进行了调查。进行了半结构化访谈，内容涉及育种者状况、育种系统和抗生素使用。通过多重对应分析和层次分类分析，建立了种源类型学。繁殖者主要为富拉尼族（71.4 +/- 8.9%），几乎全部未接受过正规教育（96.9 +/- 3.4%）。牛群主要由单一品种组成，分别为Borgou（76.4 +/- 8.1%）和富拉尼Zebu（16.0 +/- 7.0%）。有些牧群是混合的。奶牛养殖中使用的抗生素类群为四环素类、β -内酰胺类、磺胺类、氨基糖苷类和大环内酯类，分别为100%、69.4 +/- 9.1%、56.1 +/- 9.8%、44.9 +/- 9.8%和34.7 +/- 9.4%。这些药品来自当地市场（59.0 +/- 15.4%）和兽医药房（41.0 +/- 15.4%）。它们主要用于治疗呼吸系统疾病、跛行、乳腺炎、脐炎和新生儿肠炎以及皮肤病。只有49.0 +/- 9.9%的养殖者寻求兽医服务治疗动物，92.9 +/- 5.1%的养殖者不尊重抗生素停药时间。这些做法表明，牛肉被抗生素残留物污染和选择耐药细菌都是可以预期的，从而对消费者的健康产生不利影响。
This study's aim is to inventory antibiotics used in cattle in North-East Benin and assess risk practices that could be the cause of both food chain contamination by antibiotic residues and selection of antibiotic-resistant bacteria in animals and humans. A survey was conducted among 98 cattle breeders in the districts of Banikoara, Kandi, Bembereke, and Kalale in North Benin. Semi-structured interviews were conducted, covering breeder status, breeding system, and antibiotic use. Multiple correspondence analysis and hierarchical classification analysis were conducted to establish a breeder typology. Breeders mainly belonged to the Fulani ethnic group (71.4 +/- 8.9%) and almost all of them received no formal education (96.9 +/- 3.4%). Cattle herds were mainly composed of a single breed, the Borgou (76.4 +/- 8.1%) or the Fulani Zebu (16.0 +/- 7.0%). Some herds were mixed. Antibiotics groups used in cattle breeding were tetracyclines, beta-lactams, sulfonamides, aminoglycosides, and macrolides, used by respectively 100%, 69.4 +/- 9.1%, 56.1 +/- 9.8%, 44.9 +/- 9.8%, and 34.7 +/- 9.4% of breeders. These drugs were purchased in local markets (59.0 +/- 15.4%) and veterinary pharmacy (41.0 +/- 15.4%). They were mainly used against respiratory diseases, lameness, mastitis, omphalitis and neonatal enteritis, and skin diseases. Only 49.0 +/- 9.9% of breeders seek veterinary services to treat animals and 92.9 +/- 5.1% of them did not respect antibiotic withdrawal times. These practices suggest that both contamination of bovine meat with antibiotic residues and selection of resistant bacteria are to be expected, resulting in adverse health effects on consumers.