Variations in societal characteristics of spatial disease clusters: examples of colon, lung and breast cancer in Japan.
Variations in societal characteristics of spatial disease clusters: examples of colon, lung and breast cancer in Japan.
复制标题
DOI：
10.1186/1476-072x-4-16
复制
发表时间：
2005-06-14
影响因子：
4.9
通讯作者：
Takano, Takehito
中科院分区：
文献类型：
--
作者：
Fukuda, Yoshiharu;Umezaki, Masahiro;Takano, Takehito
背景：空间分析和生态学研究对流行病学和公共卫生至关重要。本研究结合这两种方法来确定日本选定的癌症类型的空间聚集性，并确定其关注聚集性的社会特征。结果：利用日本1993年至1998年的市政数据(N=3360)，通过空间扫描统计确定了男性结肠癌和肺癌以及女性乳腺癌高死亡率的空间聚集性，并根据社会经济指标和人口密度将城市划分为四个社会聚集区(城市富裕、郊区、农村贫穷和杂乱)。分别确定了肺癌、结肠癌和乳腺癌的五个、七个和四个死亡率集群。在结肠癌和乳腺癌方面，除一个聚集区外，大多数城市都属于一个单一的社会聚集区(富裕的城市)。与肺癌死亡聚集区相关的城市属于不同的社会聚集区。结论：结肠癌和乳腺癌死亡率的上升可以用与城市化相关的同质性社会特征来解释，尽管也有死亡率较高的特殊地区。肺癌死亡率的地区差异似乎是由于异质性因素造成的。这些发现和在本研究中进行的分析将有助于制定全国性和地区性癌症预防战略。
BACKGROUND: Spatial analyses and ecological studies are essential for epidemiology and public health. The present study combining these two methods was performed to identify spatial clusters of selected types of cancer in Japan and to determine their societal characteristics focusing on homogeneity among clusters.RESULTS: Spatial clusters of high mortality rates of male colon and lung cancer and of female breast cancer were identified by the spatial scan statistic using Japanese municipal data (N = 3360) from 1993 to 1998 and also municipalities were divided into four societal clusters based on socioeconomic indicators and population density (urban-rich, suburban, rural-poor, and clutter). Five, seven, and four mortality clusters were identified for lung, colon and breast cancer, respectively. For colon and breast cancer, most municipalities of all except one cluster were included in a single societal cluster (urban-rich). The municipalities associated with mortality clusters for lung cancer belonged to various societal clusters.CONCLUSION: Increased mortality rates of colon and breast cancer can be explained by homogenous societal characteristics related to urbanisation, although there were exceptional areas with higher mortality rates. The regional variation in lung cancer mortality rate appeared to be due to heterogeneous factors. These findings and the analysis performed in the present study will contribute to both nationwide and region-specific cancer prevention strategies.