Tripping the HCN breaker.
Tripping the HCN breaker.
复制标题
使 HCN 断路器跳闸。
DOI：
10.1016/j.neuron.2009.06.003
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发表时间：
2009
期刊：
影响因子：
16.2
通讯作者：
Pan,JenniferQian
中科院分区：
文献类型：
--
作者：
Lipscombe,Diane;Pan,JenniferQian
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate neuronal excitability, pacemaking, dendritic integration, and homeostatic plasticity and are culprits in aberrant neuronal activity in certain epilepsies. In this issue ofNeurontwo manuscripts (Santoro et al. and Zolles et al.) report that HCN channel gating and expression are controlled by Trip8b (Pex5R) but with a bidirectional spin.
