Cowpea Mosaic Virus
Cowpea Mosaic Virus
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DOI：
10.1016/b978-012374410-4.00562-8
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发表时间：
2008-07-30
期刊：
影响因子：
--
通讯作者：
Lomonossoff GP
中科院分区：
文献类型：
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作者：
Lomonossoff GP
豌豆花叶病毒(CPMV)是冠状病毒属的模式成员，由冠状病毒科3个属之一组成。CPMV基因组由两个正链RNA分子组成，分别包裹在由两种类型的外壳蛋白各60个拷贝组成的等长颗粒中。自最初分离以来，CPMV已经从遗传和结构角度得到了广泛的研究，并已成为植物病毒通过合成和加工前体多蛋白来表达其基因组的范例。在这一点上，以及在其颗粒结构，CPMV类似于科的其他成员。最近，该病毒已被用于许多生物技术应用。
Cowpea mosaic virus (CPMV) is the type member of the genus Comovirus, which comprises one of three genera of the family Comoviridae. The genome of CPMV consists of two molecules of positive-strand RNA, which are separately encapsidated in isometric particles consisting of 60 copies each of two types of coat protein. Since its initial isolation, CPMV has been extensively studied from both a genetic and structural point of view and has become a paradigm for plant viruses that express their genome through the synthesis and processing of precursor polyproteins. In this regard, as well as in its particle structure, CPMV resembles other members of the family Picornaviridae. More recently, the virus has been used for a number of biotechnological applications.