Factors affecting the transfer of organochlorine pesticide residues to breastmilk
Factors affecting the transfer of organochlorine pesticide residues to breastmilk
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DOI：
10.1016/s0045-6535(00)00149-1
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发表时间：
2001-04-01
期刊：
影响因子：
8.8
通讯作者：
Hay, AWM
中科院分区：
文献类型：
--
作者：
Harris, CA;Woolridge, MW;Hay, AWM
对监测母乳中有机氯农药残留的现有研究进行了审查，以确定共同因素是否决定了这些残留物的转移程度。对英语文献进行了结构性审查。使用结构化方案对论文进行审查和评估。初步确定了总共77篇论文，其中46篇包含与可能影响残留物转移到母乳中的因素有关的结论。由于调查结果的多样性，对论文进行了进一步筛选，只包括那些报告了与母亲选择和母乳取样程序有关的最低限度背景信息的论文。只有8份文件被认为载有充分的资料。在评估有机氯农药残留物转移到母乳中的情况时，年龄、产次/前一次哺乳期长短、脂肪动员和取样时间被确定为最有可能考虑的因素。这篇综述强调了在不使用可比抽样程序的情况下评估母乳污染物趋势的困难。皇冠版权所有（C）2001由爱思唯尔科学有限公司出版。保留所有权利。
Existing studies monitoring organochlorine pesticide residues in breastmilk were examined to identify whether common factors determine the extent of transfer of these residues. A structured review of the English language literature was conducted. Papers were reviewed and assessed using a structured protocol. A total of 77 papers were initially identified, 46 of which contained conclusions relating to the factors which may affect the transfer of residues into breastmilk. Owing to the diversity of findings, papers were screened further to include only those in which a minimum of background information relating to selection of mothers and to milk sampling procedures were reported. Only eight papers were deemed to contain adequate information. Age, parity/length of previous lactation, fat mobilisation and the time of sampling were identified as the most likely factors to be considered when assessing transfer of organochlorine pesticide residues into breastmilk. This review highlights the difficulties of assessing trends in breastmilk contaminants where comparable sampling procedures are not used. Crown Copyright (C) 2001 Published by Elsevier Science Ltd. All rights reserved.