Development of paper substrate for paper spray MS in high-sensitivity analysis of biological samples.
Development of paper substrate for paper spray MS in high-sensitivity analysis of biological samples.
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DOI：
10.4155/bio-2018-0199
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发表时间：
2018-11
期刊：
影响因子：
1.8
通讯作者：
Weiwei Han;Yajun Zheng;Theoneste Muyizere;Zhiping Zhang
中科院分区：
文献类型：
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作者：
Weiwei Han;Yajun Zheng;Theoneste Muyizere;Zhiping Zhang
纸喷雾（PS）已被证明是一个有前途的直接质谱分析。在PS工艺中，纸基是决定PS-MS最终性能的关键因素，因此纸基的改性备受关注。本文系统地介绍了PS纸基材料的研究进展。本文综述了各种商品化和改性的纸张，着重介绍了纸基改性的物理和化学方法。讨论了改性纸基质在生物样品分析中的应用。指出了PS纸基材料的发展方向。
Paper spray (PS) has demonstrated a promising future for direct mass spectrometric analysis. In the process of PS, paper substrate has been demonstrated as a crucial factor in determining the final performance of PS-MS, and therefore much attention is paid to modification of paper substrate. In this review, we systematically introduce the development of paper substrate for PS. Various commercial and modified papers are comprehensively reviewed, and much effort is focused on some physical and chemical approaches for modification of paper substrate. The application of modified paper substrates to biological sample analyses is discussed. The future promising directions of paper substrate for PS are highlighted.