Vulvovaginal and ocular involvement and treatment in female patients with Stevens-Johnson syndrome and toxic epidermal necrolysis: A review.
Vulvovaginal and ocular involvement and treatment in female patients with Stevens-Johnson syndrome and toxic epidermal necrolysis: A review.
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DOI：
10.1016/j.ijwd.2021.08.012
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发表时间：
2021-12
影响因子：
--
通讯作者：
Pasieka H
中科院分区：
文献类型：
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作者：
Magone MT;Maiberger M;Clayton J;Pasieka H
Stevens-Johnson综合征（SJS）和中毒性表皮坏死松解症（TEN）是严重的皮肤药物不良反应，其特征为表皮脱落和粘膜受累。SJS/TEN在女性患者中更常见，在眼部和外阴区域有独特的发现。早期识别和干预，以及长期随访，是至关重要的，以防止毁灭性的疤痕和后遗症。本文综述了SJS/TEN的外阴和眼部表现，并介绍了目前对女性患者的治疗建议，需要皮肤科，眼科和妇科之间的密切协商和合作。
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious adverse cutaneous drug reactions, characterized by epidermal detachment and mucous membrane involvement. SJS/TEN is more common in female patients, with unique findings in the ocular and vulvar regions. Early recognition and intervention, as well as long-term follow-up, are crucial to prevent devastating scarring and sequelae. This review examines the vulvar and ocular manifestations of SJS/TEN and describes the current treatment recommendations for female patients, requiring close consultation and collaboration among dermatology, ophthalmology, and gynecology.