The 2019 FASEB Science Research Conference on Ion Channel Regulation: Molecules to Disease, July 7-12, 2019, Lisbon, Portugal.
The 2019 FASEB Science Research Conference on Ion Channel Regulation: Molecules to Disease, July 7-12, 2019, Lisbon, Portugal.
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2019 年 FASEB 离子通道调控科学研究会议：分子与疾病，2019 年 7 月 7-12 日，葡萄牙里斯本。
DOI：
10.1096/fj.202000367
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Khanna,Rajesh
中科院分区：
文献类型：
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作者：
Colecraft,HenryM;Khanna,Rajesh
2019年7月7日至12日，在葡萄牙里斯本，《离子通道调控会议：分子与疾病》在里斯本万豪酒店举行。会议重点讨论了离子通道调节机制的最新研究，它对不同类型细胞生理的影响，以及靶向离子通道调节在药物开发中的潜力。在人类基因组中，离子通道控制着许多重要的细胞和生理过程，包括神经元放电和突触传递、肌肉收缩、激素分泌、体液平衡、胃酸化和基因表达。离子通道的遗传或从头突变(所谓的通道病)是人类毁灭性疾病的基础，如癫痫、自闭症、慢性疼痛、囊性纤维化、糖尿病和致命性心律失常。毫不奇怪，离子通道不仅是现有疗法的重要靶点，而且在未来的药物开发努力中也具有巨大的未开发潜力。FASEB SRC在这一重要研究领域的发现引擎方面发挥了至关重要的作用，它在集中的、紧张的一周内将来自不同领域的研究人员聚集在一起，分享离子通道监管的最新和最令人兴奋的发展，目的是跨学科共享信息，建立新的个人联系，并促进未来的合作。自2003年成立以来，该会议每隔一年举行一次，可以说是2019年离子通道领域最重要的会议。它是来自美国、加拿大、欧洲、亚洲和全球其他地区的顶尖科学家展示和讨论他们最新和最重要的研究的重要论坛。在四天半的会议中，有32场长篇演讲，2场主旨演讲，21场从提交的摘要中挑选出来的简短演讲，以及66张海报演示文稿。令人印象深刻的是，有*通讯作者：hc2405@cumc的全面参与。哥伦比亚。每年，一系列的科学研究会议(SRCs)都是由美国实验生物学学会联合会(FASE B)主办的，FASE B是一个由29个研究学会组成的非营利性联合会，代表130,000名科学家，它允许实验生物学家在一个放松的、合议的气氛中会面，并探索当前研究领域的新方法。社论、论文、致编辑的信和其他组成前置部分的文章中表达的观点是作者的观点，不一定反映FASE B或其组成学会的观点。FASEB期刊欢迎所有观点和许多声音。我们期待着以专栏文章和/或致@FASEB期刊的读者来信的形式收到这些消息。Org.
The “Ion Channel Regulation Conference: Molecules to Disease” conference was held in Lisbon, Portugal, July 7–12, 2019 at the Lisbon Marriott Hotel. The conference focused on the latest research on mechanisms of ion channel regulation, its impact on the physiology of diverse cell types, and the potential for targeting ion channel regulation in drug development. Accounting for~ 1–2% of genes in the human genome, ion channels control many essential cellular and physiological processes including; neuronal firing and synaptic transmission, muscle contraction, hormonal secretion, fluid homeostasis, gastric acidification, and gene expression. Inherited or de novo mutations in ion channels (the so-called ‘channelopathies’) underlie devastating human diseases such as; epilepsy, autism, chronic pain, cystic fibrosis, diabetes, and lethal cardiac arrhythmias. Not surprisingly, ion channels not only represent important targets for existing therapeutics, but also hold vast untapped potential for future drug development efforts. This FASEB SRC plays a vital role in fueling the engine of discovery in this vital research area by bringing together, in a concentrated, intense week, leading investigators from diverse fields to share the latest and most exciting developments in Ion Channel Regulation, with the aim of sharing information across disciplines, establishing new personal contacts, and promoting future collaborations. This conference has taken place every other year since its inception in 2003 and was arguably the most important meeting in the ion channel field in 2019. It serves as an essential forum for leading scientists from the US, Canada, Europe, Asia and other parts of the globe to present and discuss their latest and most important research. Over the four and a half days of the meeting, there were 32 full-length talks, 2 keynote lectures, 21 short talks chosen from submitted abstracts, and 66 poster presentations. Impressively, there was full participation by* corresponding author: hc2405@ cumc. columbia. edu; Each year, a series of Science Research Conferences (SRCs) are sponsored by The Federation of American Societies for Experimental Biology (FASEB), a non-profit federation of 29 research societies representing 130,000 scientists, that allows experimental biologists to meet in a relaxing, collegial atmosphere and explore new approaches to current research areas.The opinions expressed in editorials, essays, letters to the editor, and other articles comprising the Up Front section are those of the authors and do not necessarily reflect the opinions of FASEB or its constituent societies. The FASEB Journal welcomes all points of view and many voices. We look forward to hearing these in the form of op-ed pieces and/or letters from its readers addressed to journals@ faseb. org.