Factors associated with tuberculosis treatment default and completion at the Effia-Nkwanta Regional Hospital in Ghana

Factors associated with tuberculosis treatment default and completion at the Effia-Nkwanta Regional Hospital in Ghana
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DOI:
10.1016/j.trstmh.2005.06.011
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发表时间:
2005-11-01
影响因子:
2.2
通讯作者:
Afenyadu, GY
Afenyadu, GY
中科院分区:
医学4区
文献类型:
--
作者:
Dodor, EA;Afenyadu, GY

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2000年1月至2001年12月期间,埃菲亚-恩宽塔地区医院的结核病患者拖欠治疗的比例为13.9%。因此,本研究旨在评估与医院结核病治疗违约和完成相关的因素。研究的第一部分包括针对卫生工作者、违约者和非违约者的三个单独的焦点小组讨论。收集到的信息用于设计一份调查问卷,对从机构结核病登记册中选出的违约者和非违约者进行调查。进行单变量逻辑回归分析以确定与治疗违约相关的重要因素。 P < 0.05 视为具有统计学意义。治疗违约与每月收入(P = 0.03)、购买补充药物的能力(P = 0.008)、社会支持的可用性(P = 0.005)以及治疗期间与他人相关的问题(P = 0.01)显着相关。患者和医护人员之间的融洽关系是完成治疗的主要动力,而经济困难则是未能接受治疗的主要原因。确定本研究中发现的与治疗开始时结核病患者违约相关的特征可能有助于提高在医院登记接受治疗的患者的依从性。 (c) 2005 年皇家热带医学和卫生学会。由爱思唯尔有限公司出版。保留所有权利。
The level of defaulting from treatment among tuberculosis (TB) patients at the Effia-Nkwanta Regional Hospital between January 2000 and December 2001 was 13.9%. This study was therefore designed to assess factors associated with TB treatment default and completion at the hospital. The initial part of the study consisted of three separate focus group discussions for health workers, defaulters and non-defaulters. The information collected was used to design a questionnaire that was administered to defaulters and non-defaulters selected from the Institutional TB Register. Univariate logistic regression analysis was performed to identify significant factors associated with treatment default. Statistical significance was taken as P < 0.05. Default from treatment was significantly associated with income per month (P = 0.03), ability to afford supplementary drugs (P = 0.008), availability of social support (P = 0.005) and problems relating with others while on treatment (P = 0.01). A cordial relationship between patients and health staff was the main motivating factor for completion of treatment, whilst financial difficulty was the main reason for defaulting from treatment. Determination of the characteristics found to be associated with defaulting in this study among TB patients at the start of treatment may be helpful in improving compliance among patients registered for treatment at the hospital. (c) 2005 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.