Cohort Profile: The Gateshead Millennium Study

Cohort Profile: The Gateshead Millennium Study
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DOI:
10.1093/ije/dyq015
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发表时间:
2011-04-01
影响因子:
7.7
通讯作者:
Adamson, Ashley J.
Adamson, Ashley J.
中科院分区:
医学1区
文献类型:
--
作者:
Parkinson, Kathryn N.;Pearce, Mark S.;Adamson, Ashley J.

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盖茨黑德千禧年婴儿研究(GMBS)起源于观察到婴儿期体重增长速度慢于预期,传统上被称为未能茁壮成长,但最近被称为“体重下降”,从未得到令人满意的解释。以前的许多研究都存在方法问题。第一个是使用获得的体重标准来识别婴儿期体重缓慢增加,这混淆了出生后体重增加不良与出生前体重增加不良。第二个是使用儿童的参考样本,导致选择偏差。第三个是在已经确定体重增加不佳后,使用父母的回顾性描述。因此,GMBS最初的目的是调查体重动摇的前因在一个基于人群的前瞻性研究,解决了以前的研究的主要方法学问题。
The Gateshead Millennium Baby Study (GMBS) originated from the observation that slower than expected weight gain in infancy, traditionally known as failure to thrive, but more recently as ‘weight faltering’, had never been satisfactorily explained. There were methodological problems associated with much previous research. The first was the use of attained weight criteria to identify slow weight gain in infancy, which confounds poor postnatal weight gain with poor prenatal weight gain. The second was the use of referred samples of children, leading to selection biases. The third was the use of retrospective accounts from parents after poor weight gain had already been identified. The GMBS was thus originally designed to investigate the antecedents of weight faltering in a population-based prospective study that addressed the main methodological problems of previous research.