The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
复制标题
DOI：
10.1073/pnas.0307195101
复制
发表时间：
2004-05-25
影响因子：
11.1
通讯作者：
Rainey, PB
中科院分区：
文献类型：
--
作者：
MacLean, RC;Bell, G;Rainey, PB
由于拮抗性多效性或突变积累，生态专业化的进化预计会带来成本。一般来说，很难区分这两种可能性。在这里，我们证明，定植于空间结构微观世界的空气-肉汤界面的荧光假单胞菌的生态位专业基因型的实验进化伴随着碳分解代谢减少方面的多效性适应成本。空间结构微观世界中的长期选择导致专业化成本下降，而专业化带来的好处却没有损失。专业化成本的下降可以通过专业谱系内的补偿性适应或专业谱系之间的克隆竞争来解释。这些结果为专业化成本的相互冲突的解释提供了可能的解释。
The evolution of ecological specialization is expected to carry a cost, due to either antagonistic pleiotropy or mutation accumulation. In general, it has been difficult to distinguish between these two possibilities. Here, we demonstrate that the experimental evolution of niche-specialist genotypes of the bacterium Pseudomonas fluorescens that colonize the air-broth interface of spatially structured microcosms is accompanied by pleiotropic fitness costs in terms of reduced carbon catabolism. Prolonged selection in spatially structured microcosms caused the cost of specialization to decline without loss of the benefits associated with specialization. The decline in the cost of specialization can be explained by either compensatory adaptation within specialist lineages or clonal competition among specialist lineages. These results provide a possible explanation of conflicting accounts for the cost of specialization.