Reaction of calcium phosphate cements with different amounts of tetracalcium phosphate and dicalcium phosphate anhydrous
Reaction of calcium phosphate cements with different amounts of tetracalcium phosphate and dicalcium phosphate anhydrous
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DOI：
10.1002/(sici)1097-4636(19990915)46:4
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发表时间：
1999-09-15
期刊：
影响因子：
--
通讯作者：
Suzuki, K
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文献类型：
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作者：
Ishikawa, K;Takagi, S;Suzuki, K
为进一步了解磷酸钙骨水泥（CPC）的固化反应及影响CPC性能的因素，制备了不同磷酸四钙（TTCP）和无水磷酸二钙（DCPA）含量（TTCP/DCPA摩尔比为0.25 ~ 2.00）的CPC。定量的X-射线衍射图，傅里叶变换红外光谱，和径向拉伸强度的设置质量测量沿着与CPC悬浮液的pH值测量。缺钙羟基磷灰石（d-HAP）的钙磷酸盐的摩尔比约为1.5，最初形成的CPC设置组成的TTCP和DCPA的等摩尔混合物。随着孵育时间的增加，这逐渐转化为化学计量的KA（s-HA）。当CPC中含有过量的TTCP时，在初始阶段形成s-HA。相反，当CPC含有过量的DCPA时，s-HAP的成熟缓慢。固定CPC的最高机械强度与TTCP和DCPA的等摩尔混合物相关，并且机械强度随着TTCP/DCPA摩尔比偏离1.00而降低。因此，我们得出结论，固化反应和所得到的固化质量的性质取决于TTCP和DCPA的摩尔比。(C)1999年John Wiley & Sons，Inc.
Calcium phosphate cements (CPCs) with different amounts of tetracalcium phosphate (TTCP) and dicalcium phosphate anhydrous (DCPA) (TTCP/DCPA molar ratio from 0.25 to 2.00) were prepared to further understand the setting reaction and the factors that could influence the properties of CPCs. Quantitative X-ray diffraction patterns, Fourier transform IR spectra, and diametral tensile strength of the set mass were measured along with pH measurements of the CPC suspension. Calcium-deficient hydroxyapatite (d-HAP) with a calcium to phosphate molar ratio of approximately 1.5 was formed initially in the CPC setting consisting of an equimolar mixture of TTCP and DCPA. This gradually transformed into stoichiometric KA (s-HA) with increasing incubation time. The s-HA was formed in the initial stage when the CPC contained an excess amount of TTCP. In contrast, maturation to s-HAP was slow when the CPC contained excess amounts of DCPA. The highest mechanical strength of set CPC was associated with an equimolar mixture of TTCP and DCPA, and the mechanical strength decreased as the TTCP/DCPA molar ratio deviated from 1.00. We concluded, therefore, that the setting reaction and the nature of the resulting set mass are dependent on the molar ratios of TTCP and DCPA. (C) 1999 John Wiley & Sons, Inc.*.