Software for constructing and verifying pedigrees within large genealogies and an application to the old order Amish of Lancaster County
Software for constructing and verifying pedigrees within large genealogies and an application to the old order Amish of Lancaster County
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DOI：
10.1101/gr.8.3.211
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发表时间：
1998-03-01
期刊：
影响因子：
7
通讯作者：
Schaffer, AA
中科院分区：
文献类型：
--
作者：
Agarwala, R;Biesecker, LG;Schaffer, AA
本文描述了PedHunter，这是一个便于在大型家谱中创建和验证家谱的软件包。医学遗传学中的一个常见问题是将远亲与血统联系起来。PedHunter使用图论的方法来解决两种版本的谱系联系问题以及其他谱系分析问题。这些系谱由PedHunter以链接格式的文件形式生成，可供链接分析使用。对于所有的计算，PedHunter使用家谱数据的关系数据库，带有指定格式的表格。PedHunter的功能和用途通过使用Amish系谱数据库(AGDB)的例子来说明，AGDB是为宾夕法尼亚州兰开斯特县的旧秩序Amish社区创建的。
This paper describes PedHunter, a software package that facilitates creation and verification of pedigrees within large genealogies. A frequent problem in medical genetics is to connect distant relatives with a pedigree. PedHunter uses methods from graph theory to solve two versions of the pedigree connection problem for genealogies as well as other pedigree analysis problems. The pedigrees are produced by PedHunter as files in LINKAGE format ready for linkage analysis. PedHunter uses a relational database of genealogy data, with tables in specified format, for all calculations. The functionality and utility of PedHunter are illustrated by examples using the Amish Genealogy Database (AGDB), which was created for the Old Order Amish community of Lancaster County, Pennsylvania.