Antibiotic Resistance in Nosocomial Respiratory Infections
Antibiotic Resistance in Nosocomial Respiratory Infections
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DOI：
10.1016/j.cll.2014.02.004
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发表时间：
2014-06-01
影响因子：
1.7
通讯作者：
Relich, Ryan F.
中科院分区：
文献类型：
--
作者：
Denys, Gerald A.;Relich, Ryan F.
院内呼吸道感染是严重基础疾病患者中最常见的获得性感染，是该患者人群中发病率和死亡率较高的原因。多药耐药（MDR）病原体与医院获得性肺炎（HAP）和呼吸机相关性肺炎（VAP）相关。本文介绍了耐药细菌相关的HAP和VAP的病原学、流行病学、发病机制、诊断和治疗。
Nosocomial respiratory infections are the most common acquired infections in patients with severe underlying conditions and are responsible for high morbidity and mortality in this patient population. Multidrug-resistant (MDR) pathogens are associated with hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP). This article describes the etiology, epidemiology, pathogenesis, diagnosis, and treatment of HAP and VAP associated with antibiotic-resistant bacterial pathogens.