Effects of yoga program on quality of life and affect in early breast cancer patients undergoing adjuvant radiotherapy: A randomized controlled trial

Effects of yoga program on quality of life and affect in early breast cancer patients undergoing adjuvant radiotherapy: A randomized controlled trial
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DOI:
10.1016/j.ctim.2009.06.004
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发表时间:
2009-10-01
影响因子:
3.6
通讯作者:
Rao, Nalini
Rao, Nalini
中科院分区:
医学3区
文献类型:
--
作者:
Vadiraja, H. S.;Rao, M. Raghavendra;Rao, Nalini

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目的:本研究比较了一个综合的瑜伽计划与简短的支持性治疗乳腺癌门诊患者接受辅助放疗在cancer centre.Methods的效果:88阶段II和III乳腺癌门诊患者随机分配到接受瑜伽(n = 44)或简短的支持性治疗(n = 44)之前,他们的放疗治疗。干预组每天进行60分钟的瑜伽练习,对照组每10天进行一次支持性治疗。评估包括欧洲癌症治疗研究组织-生活质量(EORTCQoL C30)功能量表和积极和消极情绪量表(PANAS)。评估在基线和6周后的放射治疗treatment.Results:一个意向治疗GLM重复测量方差分析显示,随着时间的推移,积极的影响,消极的影响,情绪功能和社会功能的显着差异。积极情感有显著改善(ES = 0.59,p= 0.007,95%CI 1.25至7.8),情绪功能(ES = 0.71,p = 0.001,95%CI 6.45 - 25.33)和认知功能(ES=0.48,p=0.03,95%CI 1.2 - 18.5),以及负面情绪的减少(ES=0.84,p
Objectives: This study compares the effects of an integrated yoga program with brief supportive therapy in breast cancer outpatients undergoing adjuvant radiotherapy at a cancer centre.Methods: Eighty-eight stage II and III breast cancer outpatients were randomly assigned to receive yoga (n = 44) or brief supportive therapy (n = 44) prior to their radiotherapy treatment. Intervention consisted of yoga sessions tasting 60 min daily while the control group was imparted supportive therapy once in 10 days. Assessments included European Organization for Research in the Treatment of Cancer-Quality of Life (EORTCQoL C30) functional scales and Positive and Negative Affect Schedule (PANAS). Assessments were done at baseline and after 6 weeks of radiotherapy treatment.Results: An intention to treat GLM repeated measures ANOVA showed significant difference across groups over time for positive affect, negative affect and emotional function and social function. There was significant improvement in positive affect (ES = 0.59, p= 0.007, 95%CI 1.25 to 7.8), emotional function (ES = 0.71, p = 0.001, 95%CI 6.45 to 25.33) and cognitive function (ES=0.48, p=0.03, 95%CI 1.2 to 18.5), and decrease in negative affect (ES=0.84, p