Effect of disease-modifying therapies on brain volume in relapsing-remitting multiple sclerosis: Results of a five-year brain MRI study
Effect of disease-modifying therapies on brain volume in relapsing-remitting multiple sclerosis: Results of a five-year brain MRI study
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DOI：
10.1016/j.jns.2011.08.034
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发表时间：
2012-01-15
影响因子：
4.4
通讯作者：
Zak, Imad
中科院分区：
文献类型：
--
作者：
Khan, Omar;Bao, Fen;Zak, Imad
目的：比较疾病缓解疗法 (DMT) 对复发缓解型多发性硬化症 (RRMS) 患者脑容量损失的长期影响。方法：我们进行了一项研究，探讨每日醋酸格拉替雷 (GA)、每周一次低剂量干扰素 β (LD-IFNB) 和高剂量高频干扰素 β 病 (HD-IFNB) 对 RRMS 患者 5 年来脑容量损失的影响。所有患者之前均未接受过治疗，且有病程
Objective: To compare the long-term effect of disease-modifying therapies (DMT) on brain volume loss in relapsing-remitting MS (RRMS) patients.Methods: We conducted a study to examine the effect of daily glatiramer acetate (GA), weekly low dose interferon beta (LD-IFNB), and high-dose high-frequency interferon beta disease (HD-IFNB) on brain volume loss over 5 years in RRMS patients. All patients were previously treatment nave, had disease duration