When being alone is enough: noncanonical functions of canonical bacterial quorum-sensing systems.
When being alone is enough: noncanonical functions of canonical bacterial quorum-sensing systems.
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DOI：
10.2217/fmb-2016-0066
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发表时间：
2016-10
影响因子：
3.1
通讯作者：
Bobbi Xayarath;N. Freitag
中科院分区：
文献类型：
--
作者：
Bobbi Xayarath;N. Freitag
许多细菌病原体能够通过细菌信号和细胞间通信过程（通常称为群体感应（QS））检测位于其周围生态位内的其他细菌的存在。QS系统现在通常被描述为细菌群体协调各种生理功能以增强群落生存所表现出的集体行为。然而，QS系统也涉及到不同于细菌细胞密度测量的各种过程。这篇综述将强调规范QS系统的非规范适应，这些系统已经进化到使细菌能够检测群体内的非自我个体或检测密闭空间的占用。
A number of bacterial pathogens are capable of detecting the presence of other bacteria located within their surrounding niche through a process of bacterial signaling and cell-to-cell communication commonly referred to as quorum sensing (QS). QS systems are commonly now described in the context of collective behaviors exhibited by groups of bacteria coordinating diverse arrays of physiological functions to enhance survival of the community. However, QS systems have also been implicated in a variety of processes distinct from the measure of bacterial cell density. This review will highlight noncanonical adaptations of canonical QS systems that have evolved to enable bacteria to detect nonself individuals within a population or to detect occupation of confined spaces.