2 CASES OF APLASTIC ANAEMIA ASSOCIATED WITH TUMOURS OF THYMUS
2 CASES OF APLASTIC ANAEMIA ASSOCIATED WITH TUMOURS OF THYMUS
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DOI：
10.1136/jcp.15.3.264
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发表时间：
1962-01-01
影响因子：
3.4
通讯作者：
OGORMAN, P
中科院分区：
文献类型：
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作者：
BARNES, RDS;OGORMAN, P
本文报告再生障碍性贫血合并胸腺肿瘤两例。病例1患者患有全细胞减少性再生障碍性贫血，并接受ACTH治疗。尸检显示骨髓再生。本例的胸腺瘤不常见，因为胸腺退化伴脂肪替代，这可能与促肾上腺皮质激素有关。病例2最初为纯红细胞性贫血，但由于感染很少有产生白细胞增多的倾向，尸检发现胸腺淋巴上皮瘤。回顾了以往报道的病例，并讨论了促肾上腺皮质激素在治疗中的作用。
Two cases are presented in which aplastic anemia was associated with thymus tumors. In Case 1 the patient had a pancytopenic aplastic anemia and was treated with ACTH. The marrow showed regeneration at necropsy. The thymoma in this case was unusual as there was thymic regression with fat replacement which may have been related to ACTH. Case 2 was initially of a pure red cell anemia with but little tendency to produce a leucocytosis in response to infection and was found at necropsy to have a. lymphoepithelioma of the thymus. Previously reported cases are reviewed and the role of ACTH in treatment is discussed.