Characterization of a microfluidic device fabricated using a photosensitive sheet
Characterization of a microfluidic device fabricated using a photosensitive sheet
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使用感光片制造的微流体装置的表征
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
Koji Suzuki
中科院分区：
文献类型：
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作者：
T. Ito;T. Kawaguchi;Hiroko Miyoshi;K. Maruyama;S. Kaneko;S. Ohya;Y. Iwasaki;O. Niwa;Koji Suzuki
我们研究了使用光敏片粘附到衬底上的微流控器件的特性。我们根据实际标准对它们进行了评估，即耐化学性、压力密封性、电阻和离子洗脱性。当我们通过切割研究粘合特性时，在后烘烤后没有样品显示出剥离。该片材在暴露于碱性溶液时急剧膨胀。由两个Pyrex衬底夹持的光敏片和两个PMMA衬底夹持的光敏片组成的微流控器件具有0.6 MPa的压力密封，当注入超纯水时能够承受0.2 MPa的压力1 h。经后烘处理后，其体积电阻率（9.7 × 1012 Ω cm）和表面电阻率（2.3 × 1011 Ω cm）均较高。钠离子被吸附到感光片上，然后逐渐解吸。通过离子交换色谱法测定，24小时内单位面积的钠离子溶出总量为8.3 × 10 - 9 mol mm-2。这些结果证实，使用光敏片制造的微流体装置适合用作某些应用的一次性装置。
We investigated the characteristics of microfluidic devices fabricated using photosensitive sheets adhered to substrates. We evaluated them in regard to practical criteria, namely chemical resistance, pressure sealing, electrical resistance and elution of ions. No samples exhibited peeling after postbaking when we investigated the adhesion characteristics by dicing. The sheet swelled dramatically on exposure to an alkaline solution. The microfluidic devices consisting of photosensitive sheet sandwiched by two Pyrex substrates and a photosensitive sheet sandwiched by two PMMA substrates had a pressure sealing of 0.6 MPa, were capable of withstanding a pressure of 0.2 MPa for 1 h when ultrapure water was injected. The sheets had a high volume resistivity (9.7 × 1012 Ω cm) and a high surface resistivity (2.3 × 1011 Ω) after postbaking. Sodium ions were adsorbed onto the photosensitive sheet and then gradually desorbed. The total amount of sodium ion elution per unit area over 24 h was 8.3 × 10−9 mol mm−2 as measured by ion exchange chromatography. These results confirm that microfluidic devices fabricated using photosensitive sheets are suitable for use as disposable devices for certain applications.