A Preliminary Study to Investigate Relaxation and Sleep-Inducing Effects of Cedrol
A Preliminary Study to Investigate Relaxation and Sleep-Inducing Effects of Cedrol
复制标题
雪松醇放松和睡眠诱导作用的初步研究
DOI：
10.11131/2016/101228
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
S. Aoki
中科院分区：
文献类型：
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作者：
T. Komori;Yuko Tamura;M. Mitsui;J. Matsui;Daisuke Uei;S. Aoki
背景：雪松醇具有放松作用，其气味可减轻压力，从而有助于各种紧张的生活情况。然而，据报道，雪松醇也会引起睡眠，这在个案中是危险的。因此，需要进行研究以确定雪松醇的放松或睡眠诱导作用是否在压力情况下诱导，以及如何仅获得前者。方法：采用交叉开放研究。受试者随机分为两组（每组n = 3）。在进行一个疗程的Kraepelin试验和在试验前后进行额外的哑铃提升后，受试者进入安慰剂或雪松醇暴露室，并以坐姿休息20分钟。进行心电图、脑电图和血压测量以及VAS评估。结果：在本研究中，没有明显的应激反应。然而，对个人的分析结果表明，雪松醇具有放松作用，在本研究所采用的条件下，它不会引起睡眠。
Background: Cedrol exhibits relaxation effects, and its scent may reduce stress, thereby contributing to various stressful life situation. However, cedrol has also been reported to induce sleep, which is dangerous by case. Therefore, studies are needed in order to determine whether the relaxation or sleep-inducing effects of cedrol are induced under stressful situation and also how to only attain the former. Method: A cross-over open study was conducted. Subjects were randomly divided into two groups (n = 3 per group). After one course of the Kraepelin test and additional dumbbell lifting before and after the test was performed, subjects entered the placebo or cedrol exposure room, and rested in a sitting position for 20 minutes. Electrocardiographic, electroencephalographic, and blood pressure measurements as well as VAS assessments were conducted. Result: In the present study, no stress response was clearly detected. However, the results of analyses with respect to individuals suggested that cedrol exhibited relaxation effects, and that it did not induce sleep under the conditions adopted in this study.