Effective removal of albumin from serum

Effective removal of albumin from serum
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DOI:
10.1002/pmic.200401235
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发表时间:
2005-10-01
期刊:
影响因子:
3.4
通讯作者:
Van Eyk, JE
Van Eyk, JE
中科院分区:
生物学3区
文献类型:
--
作者:
Colantonio, DA;Dunkinson, C;Van Eyk, JE

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The protein constituents of serum can range from grams to picograms per liter, making it tech- Received: July 16, 2004 nically difficult to achieve in-depth proteomic analysis. Removal of highly abundant proteins, Revised: December 29, 2004 such as albumin, coupled to powerful protein separation methods is required for increased Accepted: January 5, 2005 14 sample load, thus facilitating detection and identification of low-abundant proteins. We report here a chemical-based extraction method for the effective and specific removal of albumin from serum.